SPINA (Structure Parameter Inference Approach) is a method for calculating constant structure parameters of endocrine feedback control systems from hormone levels obtained in vivo.
Pilot applications have been developed for the evaluation of thyrotropic axis and fuel metabolism.
Key Features:
Calculate the thyroid's maximum secretion capacity and the sum activity of the peripheral 5'-deiodinase from the levels of TSH, FT4 and FT3 determined only once